To understand part of the mechanism of action involved in managing Hypertension, we have to understand a little bit about Nitric Oxide gas. NO is a chemical compound with the formula N2O. When Ferid Murad and Robert Furchgott discovered NO gas, they were awarded jointly the Noble Prize in medicine in 1998 for their discoveries concerning nitric oxide as a signaling molecule in the cardiovascular system. Endothelium-derived relaxing factors such as Nitric Oxide (NO) are released from the endothelial cells due to the therapeutic trauma created during and after Hijama.

Nitric Oxide Gas is a vasodilator, muscle relaxer (helps with spasms), decreases inflammation, and is anti-thrombotic. it decreases inflammation, prevents vascular stenosis, as NO inhibits the proliferation of blood vessel walls, Inhibits the aggregation of platelets, reduces smooth muscle proliferation (plays important roles in atherosclerosis throughout all stages of the disease), and decreases vascular resistance. It also contributes to the immune response because it controls neurotransmission. The negative pressure created inside the cup stretches both nerves and muscles which reduces adhesions and neural tension. Efficacy of Hijama is dependent on factors that include identifying: When to do Hijama, Where to place the cups, Order of the cups, Strength of the negative pressure (Suction), Duration of negative pressure, Style of incisions, Number of sessions… etc.

Our internal organs are interconnected with the skin through nerves and invisible pathways. It is a two-way street. Therefore, Hijama in certain areas can relieve, stimulate or treat diseased organs. This effect is identified in cases of endocrine disorders, for example. Because our internal organs are linked to the skin, we feel sometimes pain, numbness, or itchiness in some areas of the body in response to a disease we are experiencing. Our skin receptors, the mechanoreceptor, respond to Hijama by enhancing blood flow and circulation to the corresponding internal organs through the existing autonomic nerve connections.